On the Thunderbird 390, why did Ford 
      switch from a cam with 270 degrees duration / .232" lift and a 600 CFM 
      carb to a cam with 256 degrees duration / .253" lift and a 446 CFM carb in 
      1966?
      My understanding is that there was a 
      two-fold plan at work, here. Get ready for a long explanation:
      As 
      Dave mentioned, this period saw important changes to federal 
      and state auto regulations. Among these were the mandating 
      of PCV valves in NY & elsewhere, replacing old-style 
      'road draft tube' ventilation. But the biggest problem for Ford 
      was CA's new, lower standards for hydrocarbon emissions. 
      Dearborn's 4v engines were already proving somewhat problematic in this 
      regard, so it was no surprise their workhorse 390 needed some tinkering to 
      pass.
      And this was further complicated by another 
      change for '66: all grades of US pump gas had been reformulated. Premium 
      fuel, by now considered the de 
      facto touchstone of any 'personal luxury' car, 
      was bumped up from 99.0 octane to 99.8. Again, as with the 
      revised administrative laws, several Ford mills required 
      substantial rework to meet this challenge....or to take advantage of 
      it, as Ford's sales literature said at the 
time. 
      So, the base 390 4v received a new carb, 
      heads, intake, cam and valve springs....not 
      to mention the in-line fuel filter & baffled oil 
      pan. All of this was designed around twin engineering ideals of (1) improving 
      warm-up & general driveability while (2) promoting lower emissions, both at 
      idle and at speed. This latter goal proved an elusive one, 
      revealing the stalwart Autolite 4100 as the weak link - hence 1967's 
      intro of the 4300 series and 'IMCO' engineering.
      ....but that's another story. Hope this helped. :-)
      Mr 
    F